Study Hails Diabetes Drug that ‘Cuts Weight by 20%’ as ‘Game-changer’ in Battle Against Obesity

Volunteers who took the highest does of tirzepatide, 15mg, lost an average of 3st 10lb

A ‘game-changing’ diabetes drug may help obese people shed up to a fifth of their body weight, a study suggests.

Participants given a once-a-week jab of tirzepatide alongside a diet and exercise regime lost 3st 10lb on average during the 72-week trial.

The drug works by mimicking hormones in the body that help people feel full and satisfied after a meal — which are often at low levels in obese patients.

Researchers split 2,500 overweight and obese people who did not have diabetes into four groups. They were either given one of three doses of tirzepatide — 5mg, 10mg or 15mg — or a placebo.

More than half of participants in the highest dose group lost 20 per cent of their body weight by the end of the trial.

This is crucial because experts say most obese people need to lose between 15 and 20 per cent of weight to have meaningful health benefits.

The results of the study were published in the New England Journal of Medicine. 

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SOUURCE: Daily Mail, Isaan Khan and John Ely